HORDB

ID: hor001906
Uniprot ID: P45644
Protein name: Vasoactive intestinal peptide
Gene name: VIP
Organism: Meleagris gallopavo (Wild turkey)
Family: Glucagon family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Meleagris (genus), Meleagridinae (subfamily), Phasianidae (family), Galliformes (order), Galloanserae (superorder), Neognathae (infraclass), Aves (class), Coelurosauria, Theropoda, Saurischia, Dinosauria, Archosauria, Archelosauria, Sauria, Sauropsida, Amniota, Tetrapoda, Dipnotetrapodomorpha, Sarcopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity; GO:0005184 neuropeptide hormone activity
GO BP: GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway; GO:0009648 photoperiodism
GO CC: GO:0005576 extracellular region

Sequence: HSDAVFTDNYSRFRKQMAVKKYLNSVLT
Length: 28
Propeptide: MEHRGTSPLLLALALLSALCWRARALPPRGAAFPAVPRLGNRLPFDAASESDRAHGSLKSESDILQNTLPENEKFYFDLSRIIDRNDRHADGIFTTVYSHLLAKLAVKRYLHSLIRKRVSSQDSPVKRHSDAVFTDNYSRFRKQMAVKKYLNSVLTGKRSQEELNPAKLADEAEILEPSFSENYDDVSVDELLSHLPLDL
Signal peptide: MEHRGTSPLLLALALLSALCWRARA
Modification: T28 Threonine amide
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001906_AF2.pdb

hor001906_ESM.pdb

Mass:	380155	Formula:	C148H232N42O43S
Absent amino acids:	CEGIPW	Common amino acids:	KSV
pI:	10.32	Basic residues:	6
Polar residues:	9	Hydrophobic residues:	9
Hydrophobicity:	-58.93	Boman Index:	-6914
Half-Life:	3.5 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	66.07
Instability Index:	2803.57	Extinction Coefficient cystines:	2980
Absorbance 280nm:	110.37